The Young Blood Elixir for Aging

Aging affects everything, everywhere, all at once. Hair becomes gray, bones become fragile, and the heart weakens. Inside cells, DNA replication malfunctions, and proteins clump up into harmful aggregates and plaques. Natural repair mechanisms no longer work properly to replace dead or injured tissues. All this occurs more or less in sync, as if some system-wide signal has told the whole body to shut down.

In a series of studies over the last 15 years, researchers from Stanford and Harvard have shown that mice infused with blood from young mice heal faster, move quicker, think better, and remember more. The experiments reverse almost every indicator of aging the teams have probed so far. The therapy improves bone healing, fixes signs of heart failure, regrows pancreatic cells, and speeds spinal cord repair [1]. It sounds remarkable… almost like alchemy. This type of therapy is some of the most encouraging aging research in decades.

The ability to reverse aging in the body may enable us to sidestep the effects of aging that promote vulnerability to diseases, providing a unique and unexplored therapeutic approach. Researchers from UCSF have recently shown that systemic manipulations such as heterochronic parabiosis (surgically connecting a young and an old mouse together) or young blood administration can partially reverse age-related impairments in regenerative, synaptic, and cognitive functions in the aged brain. Heterochronic parabiosis studies revealed an age-dependent bi-directionality in the influence of the systemic environment, indicating that pro-youthful factors in young blood elicit rejuvenation while pro-aging factors in old blood drive pre-mature aging [2].

Blood contains a lot of information, and the most straightforward path to an aging therapy would be to pinpoint a pro-aging factor in old blood that a drug could block. Therefore, targeting pro-aging factors in old blood may provide an alternative approach to rejuvenate aging phenotypes.

Blood seems to possess almost magical properties that can restore and remodel the flesh or hasten its decay. Here at the Maharaj Institute we are interested in understanding what drives regenerative and cognitive impairments during aging, and how the effects of aging can be reversed in older people. Ultimately, our goal is to uncover immune functions that promote healthy rejuvenation as a means by which to combat age-related problems.

Please contact Dr. Maharaj at 561–752–5522, https://maharajinstitute.com. Email: info@bmscti.org

to see how they can help you measure and maintain your healthy immune system and bank your own stem cells and immune cells for future use. Office 10301 Hagen Ranch Rd. Suite 600, Boynton Beach FL 33437

References:

1. Conese M, Carbone A, Beccia E, Angiolillo A. The Fountain of Youth: A Tale of Parabiosis, Stem Cells, and Rejuvenation. Open Med (Wars). 2017; 12: 376-383. Published 2017 Oct 28. doi:10.1515/med-2017-0053

2. Villeda SA, Plambeck KE, Middeldorp J, et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med. 2014; 20(6):659-663. doi:10.1038/nm.3569